Discordance between invasive coronary flow reserve (CFR) and non-invasive myocardial flow reserve (MFR) in diffuse coronary ectasia (DCE)

Author:

Khalil Mohammed1,Alibazoglu Deniz1,Balci Cem Numan2,Hussein Rawan2,Abuwadi Abraham2,Alibazoglu Haluk2

Affiliation:

1. Heart and Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE

2. Imaging Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE

Abstract

Clinical use with evidence base for diagnostic and prognostic value of quantitative positron emission tomography(PET) myocardial perfusion imaging (MPI) in patients with known or suspected coronary artery disease has exponentially increased over the last decade. This case illustrates the very first time that stress myocardial blood flow(MBF) in absolute terms (ml/min/gram) and myocardial flow reserve(MFR) are augmented in three vessel diffuse coronary ectasia by N13-Ammonia PET MPI. Moreover, relative qualitative MPI demonstrated moderate-sized ischemia in right coronary artery territory with chronic total occlusion in middle segment; despite regional myocardial flow reserve remains above ischemic thresholds while regional stress myocardial blood flow is mildly reduced.

Publisher

British Institute of Radiology

Subject

Pharmacology (medical),Complementary and alternative medicine,Pharmaceutical Science

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