Selective boron delivery by intra-arterial injection of BSH-WOW emulsion in hepatic cancer model for neutron capture therapy

Author:

Yanagie Hironobu123,Dewi Novriana13,Higashi Syushi4,Ikushima Ichiro5,Seguchi Koji4,Mizumachi Ryoji6,Murata Yuji6,Morishita Yasuyuki7,Shinohara Atsuko8,Mikado Shoji9,Yasuda Nakahiro10,Fujihara Mitsuteru11,Sakurai Yuriko13,Mouri Kikue13,Yanagawa Masashi12,Iizuka Tomoya13,Suzuki Minoru14,Sakurai Yoshinori14,Masunaga Shin-ichiro14,Tanaka Hiroki14,Matsukawa Takehisa15,Yokoyama Kazuhito15,Fujino Takashi16,Ogura Koichi9,Nonaka Yasumasa1,Sugiyama Hirotaka1,Kajiyama Tetsuya1,Yui Sho1,Nishimura Ryohei13,Ono Koji14,Takamoto Sinichi17,Nakajima Jun318,Ono Minoru319,Eriguchi Masazumi120,Hasumi Kenichiro21,Takahashi Hiroyuki23

Affiliation:

1. Department of Innovative Cancer Therapeutics: Alpha Particle and Immunotherapeutics, Meiji Pharmaceutical University, Tokyo, Japan

2. Department of Nuclear Engineering and Management, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan

3. Cooperative Unit of Medicine and Engineering, The University of Tokyo Hospital, Tokyo, Japan

4. Department of Surgery, Kojinkai Medical City East Hospital, Miyazaki, Japan

5. Department of Radiology, Miyakonojyo Metropolitan Hospital, Miyazaki, Japan

6. Department of Pharmacology, Kumamoto Institute Branch, LSI Medience Co. Ltd, Kumamoto, Japan

7. Department of Human and Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

8. Department of Humanities, The Graduate School of Seisen University, Tokyo, Japan

9. Department of Physics, College of Industrial Technology, Nihon University, Chiba, Japan

10. Research Institute of Nuclear Engineering, University of Fukui, Fukui, Japan

11. SPG Technology Co. Ltd, Miyazaki, Japan

12. Veterinary Medical Center, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan

13. Department of Veterinary Surgery, The University of Tokyo Veterinary Hospital, Tokyo, Japan

14. Research Reactor Institute, Kyoto University, Osaka, Japan

15. Department of Epidemiology and Environmental Health, Juntendo University Graduate School of Medicine, Tokyo, Japan

16. Department of Pathological Diagnosis, Comprehensive Cancer Center, Saitama Medical University International Medical Center, Saitama, Japan

17. Department of Cardiac Surgery, Mitsui Memorial Hospital, Tokyo, Japan

18. Department of Pulmonary Surgery, The University of Tokyo Hospital, Tokyo, Japan

19. Department of Cardiac Surgery, The University of Tokyo Hospital, Tokyo, Japan

20. Department of Surgery, Shin-Yamanote Hospital, Japan Anti-Tuberculosis Association, Tokyo, Japan

21. Hasumi International Research Foundation, Tokyo, Japan

Publisher

British Institute of Radiology

Subject

Radiology Nuclear Medicine and imaging,General Medicine

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2. Development of a prompt gamma-ray detector with an 8 × 8 array LaBr 3(Ce) scintillator and a multi-pixel photon counter for boron neutron capture therapy;Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment;2023-10

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