Author:
Hamdi Yahya Al Turkey ,Aland S. Abdullah ,Harem K. Ahmed ,Bnar J. Hama Amin ,Yousif M. Mahmood ,Suhaib H. Kakamad ,Aso N. Qadir ,Hemin S. Mohammed ,Hemn H. Bayz ,Shevan M. Mustafa ,Sanaa O. Karim ,Hawbash M. Rahim ,Berun A. Abdalla ,Fahmi H. Kakamad
Abstract
Introduction
Post-COVID-19 Pulmonary Fibrosis (PC-19-PF) is among the complications following COVID-19. It is the complication that is associated with the most amount of long-term impact on the respiratory system. Different physicians approach management in different ways; therefore, we conduct a study to neatly summarize all the different management and their possible outcomes.
Methods
The databases that were searched included CINAHL, PubMed/MEDLINE, Cochrane Library, Web of Science, and EMBASE to identify English language studies published up to October 5th, 2023.
Results
Initially, the systematic search conducted brought 150 papers. Out of the 150, 13 of them were included in this study. A total of 662 patients were included in the study, all with different managements for COVID-19-induced pulmonary fibrosis. The mean age was 61.8 years. Many comorbidities were observed in patients with COVID-19-induced pulmonary fibrosis. Different treatment regimens were picked based on the different conditions of the patients but as far as antifibrotics go, Pirfenidone and Nintedanib were the most commonly used ones.
Conclusion
Both antifibrotics and steroids seemed to yield justifiable outcomes when used separately as well as when used in combination.
Reference43 articles.
1. Stuart A. Benign Tumors: Types, Causes, and Treatments [Internet]. WebMD. Available from: https://www.webmd.com/a-to-z-guides/benign-tumors-causestreatments#:~:text=Treatment%20of%20Benign%20Tumors
2. Shi Y, Wang G, Cai XP, Deng JW, Zheng L, Zhu HH, et al. An overview of COVID-19. Journal of Zhejiang University. Science. B. 2020; 21(5):343. doi:10.1631/jzus.B2000083
3. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. New England journal of medicine. 2020; 382(8):727-33. doi:10.1056/NEJMoa2001017
4. World Health Organization: WHO. Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV) [Internet]. Who.int. World Health Organization: WHO
5. 2020. Available from: https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)