1. From the Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences (R.Z., E.T., N.B., J.H., F.L., M.G.D., E.C., D.R., J.D., F.S.), Center for Biomedical Imaging, Clinical Translational Science Institute (R.Z.), and Jacobs Multiple Sclerosis Center, Department of Neurology, School of Medicine and Biomedical Sciences (C.K., D.H., B.W.G.), University at Buffalo, State University of New York, 100 High St, Buffalo, NY 14203.