Overview of Pectin-Derived Microparticles through Microfluidic Technology

Author:

Silva Pedro Brivaldo Viana da1,Fabi João Paulo1234ORCID

Affiliation:

1. Department of Food Science and Experimental Nutrition, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508000, SP, Brazil

2. Food and Nutrition Research Center (NAPAN), University of São Paulo, São Paulo 05508080, SP, Brazil

3. Food Research Center (FoRC), CEPID-FAPESP (Research, Innovation and Dissemination Centers, São Paulo Research Foundation), São Paulo 05508080, SP, Brazil

4. Food Research Center (FoRC), CEPIX-USP, University of São Paulo, São Paulo 05508000, SP, Brazil

Abstract

The scientific field of microcarrier systems has gained significant advancements, especially in drug delivery and controlled release mechanisms. This manuscript provides a comprehensive overview of the progress in developing pectin-derived microcarriers fabricated using microfluidic technology. Pectin, a naturally occurring polysaccharide, has garnered attention due to its biocompatibility, biodegradability, and ability to form hydrogels, making it an ideal candidate for forming microcarriers. The integration of microfluidic technology in synthesizing these carriers has revolutionized their design and functionality, enabling precise control over size, morphology, and encapsulation efficiency. This review systematically analyzes the methodologies employed in the microfluidic fabrication of pectin-based microparticles, highlighting the significant advantages this technology offers, such as reduced use of solvents, enhanced reproducibility, and scalability.

Funder

National Council for Scientific and Technological Development

São Paulo Research Foundation

Publisher

MDPI AG

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