Effect of Injection Parameters on the MRI and Dielectric Properties of Condensation-Cured Silicone

Author:

Cristant Conor12ORCID,Kolasangiani Kamal23,Sadanand Siddharth12,Bougherara Habiba23,Sussman Dafna124ORCID

Affiliation:

1. Department of Electrical, Computer and Biomedical Engineering, Toronto Metropolitan University, Toronto, ON M5B 2K3, Canada

2. Institute for Biomedical Engineering, Science and Technology (iBEST), St. Michael’s Hospital & Toronto Metropolitan University, Toronto, ON M5B 1T8, Canada

3. Department of Mechanical and Industrial Engineering, Toronto Metropolitan University, Toronto, ON M5B 2K3, Canada

4. Department of Obstetrics and Gynaecology, University of Toronto, Toronto, ON M5G 1E2, Canada

Abstract

Phantoms with tissue-mimicking properties play a crucial role in the calibration of medical imaging modalities, including Magnetic Resonance Imaging (MRI). Among these phantoms, silicone-based ones are widely used due to their long-term stability in MR imaging. Most of these phantoms are manufactured using traditional pour-mold techniques which often result in the production of air bubbles that can damage the phantom. This research investigates the feasibility of utilizing extrusion techniques to fabricate silicone phantoms and explores the effects of extrusion parameters including plunger speed and nozzle diameter on void content, T1 and T2 relaxation times, and dielectric properties. A custom double-syringe silicone extrusion apparatus was developed to prepare the silicone samples. The void content, relaxometry, and dielectric properties of extruded samples were measured and compared with traditional poured samples. The results show that extrusion parameters can affect the void content of the silicone samples. The presence of voids in the samples resulted in lower T1 values, indicating an inverse relationship between void content and relaxometry. This study demonstrates the potential of extrusion techniques for manufacturing silicone phantoms with reduced air bubble formation and provides valuable insights into the relationship between extrusion parameters and phantom properties.

Funder

NSERC-Discovery

Early Researcher Award

Toronto Metropolitan University Dean’s Research Fund

Publisher

MDPI AG

Subject

Polymers and Plastics,General Chemistry

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