Delayed Growth in Immature Male Rats Exposed to 900 MHz Radiofrequency

Abstract

People have been exposed to the 900 MHz mobile phone electromagnetic field for approximately 30 years. There is still no conclusion from immature rodent experiments regarding the potential effects of nonthermal radiofrequency (RF) 900 MHz continuous wave exposure during biological development. Here, we test the hypothesis that mother rats exposed at a whole-body specific absorption rate (wbSAR) occupational (Oc) limit of the International Commission on Non-Ionizing Radiation Protection for humans (0.4 W/kg) will show impairments in development, with less effect at the public (Pu) limit (0.08 W/kg). The wbSAR was estimated at 0.4 W/kg to mimic working mothers (OcM exposure) and 0.08 W/kg for non-working mothers, i.e., public (PuM exposure). This pre- and postnatal study is the first to compare public and occupational exposure limits on rat pup physical development. Litter endpoints and the descendants’ body weights and lengths were recorded regularly from birth concomitantly with the age of developmental landmarks. Male neonates showed earlier pinna ear detachment and earlier eye opening in both the OcM and PuM groups, but earlier incisor eruption only in the PuM group. The OcM-exposed males showed lower body weight as juveniles until adolescence. The OcM- and PuM-exposed descendant females showed earlier pinna ear detachment and eye opening with similar body weight. These data suggest variations in the development time of descendant rats when the mother rats received daily 900 MHz continuous waves at human limits for workers and non-workers (public).