Advances in PET/CT Imaging for Breast Cancer

Author:

de Jong Dorine1ORCID,Desperito Elise2,Al Feghali Karine3,Dercle Laurent2ORCID,Seban Romain-David45ORCID,Das Jeeban6,Ma Hong2,Sajan Abin2,Braumuller Brian2,Prendergast Conor2,Liou Connie2,Deng Aileen7,Roa Tina2,Yeh Randy6,Girard Antoine8ORCID,Salvatore Mary2,Capaccione Kathleen2

Affiliation:

1. Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA

2. Department of Radiology, Columbia University Irving Medical Center, New York, NY 10032, USA

3. RefleXion Medical, Inc., Hayward, CA 94545, USA

4. Department of Nuclear Medicine and Endocrine Oncology, Institut Curie, 92210 Saint-Cloud, France

5. Laboratory of Translational Imaging in Oncology, Paris Sciences et Lettres (PSL) Research University, Institut Curie, 91401 Orsay, France

6. Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA

7. Department of Hematology and Oncology, Novant Health, 170 Medical Park Road, Mooresville, NC 28117, USA

8. Department of Nuclear Medicine, Centre Eugène Marquis, Université Rennes 1, 35000 Rennes, France

Abstract

One out of eight women will be affected by breast cancer during her lifetime. Imaging plays a key role in breast cancer detection and management, providing physicians with information about tumor location, heterogeneity, and dissemination. In this review, we describe the latest advances in PET/CT imaging of breast cancer, including novel applications of 18F-FDG PET/CT and the development and testing of new agents for primary and metastatic breast tumor imaging and therapy. Ultimately, these radiopharmaceuticals may guide personalized approaches to optimize treatment based on the patient’s specific tumor profile, and may become a new standard of care. In addition, they may enhance the assessment of treatment efficacy and lead to improved outcomes for patients with a breast cancer diagnosis.

Publisher

MDPI AG

Subject

General Medicine

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5. Cancer Research UK (2021, August 31). Breast Cancer Statistics. Available online: https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/breast-cancer.

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