Method for Classifying Schizophrenia Patients Based on Machine Learning

Author:

Soria Carmen12,Arroyo Yoel3ORCID,Torres Ana María1,Redondo Miguel Ángel4ORCID,Basar Christoph5,Mateo Jorge1

Affiliation:

1. Institute of Technology, University of Castilla-La Mancha, 16071 Cuenca, Spain

2. Clinical Neurophysiology Service, Virgen de la Luz Hospital, 16002 Cuenca, Spain

3. Faculty of Social Sciences and Information Technology, University of Castilla-La Mancha, 45600 Talavera de la Reina, Spain

4. School of Informatics, University of Castilla-La Mancha, 13071 Ciudad Real, Spain

5. Faculty of Human and Health Sciences, University of Bremen, 28359 Bremen, Germany

Abstract

Schizophrenia is a chronic and severe mental disorder that affects individuals in various ways, particularly in their ability to perceive, process, and respond to stimuli. This condition has a significant impact on a considerable number of individuals. Consequently, the study, analysis, and characterization of this pathology are of paramount importance. Electroencephalography (EEG) is frequently utilized in the diagnostic assessment of various brain disorders due to its non-intrusiveness, excellent resolution and ease of placement. However, the manual analysis of electroencephalogram (EEG) recordings can be a complex and time-consuming task for healthcare professionals. Therefore, the automated analysis of EEG recordings can help alleviate the burden on doctors and provide valuable insights to support clinical diagnosis. Many studies are working along these lines. In this research paper, the authors propose a machine learning (ML) method based on the eXtreme Gradient Boosting (XGB) algorithm for analyzing EEG signals. The study compares the performance of the proposed XGB-based approach with four other supervised ML systems. According to the results, the proposed XGB-based method demonstrates superior performance, with an AUC value of 0.94 and an accuracy value of 0.94, surpassing the other compared methods. The implemented system exhibits high accuracy and robustness in accurately classifying schizophrenia patients based on EEG recordings. This method holds the potential to be implemented as a valuable complementary tool for clinical use in hospitals, supporting clinicians in their clinical diagnosis of schizophrenia.

Funder

UCLM-Telefonica Chair and Ministry of Economic Affairs and Digital Transformation

Publisher

MDPI AG

Subject

General Medicine

Reference68 articles.

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5. Hales, R.E. (2019). The American Psychiatric Publishing Textbook of Psychiatry, American Psychiatric Pub. [7th ed.].

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