RIAIT (Italian Registry of Allergen Immunotherapy): Protocol for a New Tool in a New Vision of Disease-Modifying Therapy for Allergists-Reference-Cited by-同舟云学术

RIAIT (Italian Registry of Allergen Immunotherapy): Protocol for a New Tool in a New Vision of Disease-Modifying Therapy for Allergists

Published:2024-08-12 Issue:8 Volume:14 Page:854
ISSN:2075-4426
Container-title:Journal of Personalized Medicine
language:en
Short-container-title:JPM

Author:

Costanzo Giovanni¹,Caruso Cristiano²³^ORCID,Paoletti Giovanni¹⁴^ORCID,Baglivo Ilaria⁵^ORCID,Colantuono Stefania⁶,Bagnasco Diego⁷⁸^ORCID,Caminati Marco⁹¹⁰^ORCID,Giovannini Mattia¹¹¹²^ORCID,Castagnoli Riccardo¹³¹⁴^ORCID,Senna Gianenrico⁹¹⁰^ORCID,Sirena Concetta¹⁵,Tosca Maria Angela¹⁶,Passalacqua Giovanni⁷⁸,Marseglia Gian Luigi¹³¹⁴,Miraglia del Giudice Michele¹⁷,Ciprandi Giorgio¹⁸^ORCID,Indolfi Cristiana¹⁷,Barberi Salvatore¹⁹,Landi Massimo²⁰^ORCID,Di Gioacchino Mario²¹^ORCID,Canonica Giorgio Walter¹⁴,Heffler Enrico¹⁴

Affiliation:

1. Personalized Medicine, Asthma and Allergy, IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy

2. UOSD Allergy and Clinical Immunology Unit, Fondazione Policlinico A. Gemelli, IRCCS, 00168 Rome, Italy

3. Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Roma, Italy

4. Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Italy

5. UOC Digestive Disease Center CEMAD, Fondazione Policlinico A. Gemelli, IRCCS, 00168 Rome, Italy

6. UOSD DH Internal Medicine and Digestive Disease, Fondazione Policlinico A. Gemelli, IRCCS, 00168 Rome, Italy

7. UO Clinica Malattie Respiratorie e Allergologia, IRCCS-AOU San Martino, 16132 Genova, Italy

8. Dipartimento di medicina interna (DIMI), Università degli Studi di Genova, 16146 Genova, Italy

9. Allergy Unit and Asthma Center, Verona Integrated University Hospital, 37134 Verona, Italy

10. Department of Medicine, University of Verona, 37124 Verona, Italy

11. Allergy Unit, Meyer Children’s Hospital IRCCS, 50139 Florence, Italy

12. Department of Health Sciences, University of Florence, 50139 Florence, Italy

13. Pediatric Unit, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy

14. Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy

15. Registro Italiano Allergen Immunotherapy (RIAIT), Via San Gregorio 12, 20124 Milan, Italy

16. Allergy Center, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy

17. Department of Woman, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy

18. Allergy Clinic, Casa di Cura Villa Montallegro, 16145 Genoa, Italy

19. Pediatric Unit, ASST-Rhodense, Rho, 20024 Milan, Italy

20. Department of Medical Sciences, Graduate School of Allergology and Clinical Immunology, University of Turin, 10126 Turin, Italy

21. Institute for Clinical Immunotherapy and Advanced Biology Treatments, University of Chieti, 66100 Chieti, Italy

Abstract

Randomized controlled trials have demonstrated responses to clinical parameters, but a significant proportion of allergy patients in real-life settings would have been excluded from such studies. Therefore, real-world research is needed, and there is a growing body of information on allergen immunotherapy’s long-term effectiveness and safety. Real-world evidence can be a valuable instrument to better understand the patient’s journey and the effectiveness and safety of therapies. For this purpose, a registry will be used for the first time in Italy to evaluate the impact of allergen immunotherapy on several outcomes, including quality of life and disease-related effects in the pediatric and adult allergic population with a socio-economic assessment and respect to real-world health.

Funder

HAL Allergy

Publisher

MDPI AG

Link

https://www.mdpi.com/2075-4426/14/8/854/pdf

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