Exploring the Contribution of Campylobacter jejuni to Post-Infectious Irritable Bowel Syndrome: A Literature Review

Author:

Imbrea Ana-Maria1ORCID,Balta Igori1ORCID,Dumitrescu Gabi1ORCID,McCleery David2,Pet Ioan1ORCID,Iancu Tiberiu3,Stef Lavinia1ORCID,Corcionivoschi Nicolae124ORCID,Liliana Petculescu-Ciochina1ORCID

Affiliation:

1. Faculty of Bioengineering of Animal Resources, University of Life Sciences King Michael I from Timisoara, 300645 Timisoara, Romania

2. Bacteriology Branch, Veterinary Sciences Division, Agri-Food and Biosciences Institute, Belfast BT4 3SD, UK

3. Faculty of Management and Rural Tourism, University of Life Sciences King Mihai I from Timisoara, 300645 Timisoara, Romania

4. Academy of Romanian Scientists, Ilfov Street, No. 3, 050044 Bucharest, Romania

Abstract

This comprehensive review investigates the specific impact of the foodborne pathogen Campylobacter jejuni (C. jejuni) on gastrointestinal health, focusing on its connection to post-infectious irritable bowel syndrome (PI-IBS). This review examines the pathogen’s pathophysiology, clinical implications and epidemiological trends using recent research and data to highlight its prevalence and association with PI-IBS. A detailed literature analysis synthesizes current research to illuminate Campylobacter’s long-lasting effects on gut microbiota and intestinal function. It provides a detailed analysis of the literature to shed light on C. jejuni’s long-term impact on gut microbiota and intestinal function. The findings suggest the need for multifaceted prevention and treatment approaches considering individual, microbial and epidemiological factors, thus contributing to a more nuanced understanding of PI-IBS following C. jejuni infection.

Funder

King Michael I University of Life Sciences in Timisoara

Publisher

MDPI AG

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