Affiliation:
1. Department of Veterinary Medicine and Animal Production, University of Naples “Federico II”, 80137 Naples, Italy
Abstract
Platelet concentrates (PCs) have become widely used in veterinary and human medicine. The PCs consist mainly of supraphysiological concentrations of platelets and, therefore, growth factors (GFs) which are stored within platelet α-granules. Among PCs, Platelet-Rich Plasma (PRP) is characterised by low-density fibrin. Research on the effect of PCs in cattle has surged in recent years; in particular, evidence has shown the positive use of PRP for treating reproductive problems, in vitro production of bovine embryos, sole ulcers and udder diseases. The aim of this report is to critically review, in accordance with the PRISMA guidelines, the available literature reporting clinical application in the bovine practice of PRP. Three bibliographic databases PubMed, Web of Science and Scopus were used for a broad search of “platelet concentrates” OR “PRP” OR “platelet-rich plasma” OR “PRF” OR “platelet-rich fibrin” AND “cows” OR “cattle”. From 1196 papers, only six met the inclusion criteria. Two papers described the use of PRP in mastitis, two papers in uterine dysfunction and two papers in ovarian dysfunction. PRP offered a low-cost, easily obtained therapeutic option and showed positive results for these patients. However, given the different pathologies and definitions involved, further studies are necessary to assess its full clinical potential.
Reference70 articles.
1. Une opportunité en paro-implantologie: Le PRF;Choukroun;Implantodontie,2001
2. Platelet-Rich Fibrin and Soft Tissue Wound Healing: A Systematic Review;Miron;Tissue Eng.-Part B Rev.,2017
3. Platelet-rich plasma preparation for regenerative medicine: Optimization and quantification of cytokines and growth factors;Amable;Stem Cell Res. Ther.,2013
4. Lange-Consiglio, A., Cazzaniga, N., Garlappi, R., Spelta, C., Pollera, C., Perrini, C., and Cremonesi, F. (2015). Platelet concentrate in bovine reproduction: Effects on in vitro embryo production and after intrauterine administration in repeat breeder cows. Reprod. Biol. Endocrinol., 13.
5. Cremonesi, F., Bonfanti, S., Idda, A., and Lange-Consiglio, A. (2020). Platelet Rich Plasma for Regenerative Medicine Treatment of Bovine Ovarian Hypofunction. Front. Vet. Sci., 7.