The Bacteriophages Therapy of Interdigital Pyoderma Complicated by Cellulitis with Antibiotic-Resistant Pseudomonas aeruginosa in a Dog

The Bacteriophages Therapy of Interdigital Pyoderma Complicated by Cellulitis with Antibiotic-Resistant Pseudomonas aeruginosa in a Dog—Case Report

Published:2023-11-05 Issue:11 Volume:10 Page:642
ISSN:2306-7381
Container-title:Veterinary Sciences
language:en
Short-container-title:Veterinary Sciences

Author:

Grecu Mariana¹,Henea Mădălina-Elena¹^ORCID,Rîmbu Cristina Mihaela²^ORCID,Simion Cătălina³,Şindilar Eusebiu-Viorel³,Solcan Gheorghe⁴^ORCID

Affiliation:

1. Department of Pharmacy, Faculty of Veterinary Medicine, Iași University of Life Sciences “Ion Ionescu de la Brad”, 8 Mihail Sadoveanu Alley, 700489 Iasi, Romania

2. Department of Microbiology, Faculty of Veterinary Medicine, Iași University of Life Sciences “Ion Ionescu de la Brad”, 8 Mihail Sadoveanu Alley, 700489 Iasi, Romania

3. Department of Surgery, Faculty of Veterinary Medicine, Iași University of Life Sciences “Ion Ionescu de la Brad”, 8 Mihail Sadoveanu Alley, 700489 Iasi, Romania

4. Department of Internal Medicine, Faculty of Veterinary Medicine, Iași University of Life Sciences “Ion Ionescu de la Brad”, 8 Mihail Sadoveanu Alley, 700489 Iasi, Romania

Abstract

Pseudomonas aeruginosa is a highly pathogenic bacterium with high pathogenicity, that can cause serious infections in all species and especially in dogs. Treatment of the infection induced by this bacterium can be a challenge considering that some strains have developed resistance to most classes of antimicrobials. The use of bacteriophages to alleviate infections caused by Pseudomonas aeruginosa has demonstrated their potential for both internal and external applications. This study aimed to illustrate the treatment with bacteriophages in bacterially complicated skin lesions that do not respond to antimicrobial therapy.

Publisher

MDPI AG

Subject

General Veterinary

Link

https://www.mdpi.com/2306-7381/10/11/642/pdf

Reference27 articles.

1. Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): Antimicrobial-resistant Pseudomonas aeruginosa in dogs and cats;Nielsen;EFSA J.,2022

2. Efficacy of experimental phage therapies in livestock;Dec;Anim. Health Res. Rev.,2020

3. Phage Therapy—Everything Old is New Again;Kropinski;Can. J. Infect. Dis. Med. Microbiol.,2006

4. Revenge of the phages: Defeating bacterial defences;Samson;Nat. Rev. Microbiol.,2013

5. Beschastnov, V.V., Egorikhina, M.N., Tulupov, A.A., Pogodin, I.E., Orlinskaya, N.Y., Antoshina, V.V., Shirokova, I.Y., and Ryabkov, M.G. (2023). Immobilization of Bacteriophages in Ex Tempore Hydrogel for the Treatment of Burn Wound Infection. Gels, 9.