myBeST—A Web-Based Survival Prognostic Tool for Women with Breast Cancer in Malaysia: Development Process and Preliminary Validation Study

Author:

Nik Ab Kadir Mohd Nasrullah1ORCID,Mohd Hairon Suhaily1ORCID,Yaacob Najib Majdi2ORCID,Yusof Siti Norbayah3,Musa Kamarul Imran1ORCID,Yahya Maya Mazuwin4,Mohd Isa Seoparjoo Azmel5,Mamat Azlan Muhammad Hafizuddin6,Ab Hadi Imi Sairi7

Affiliation:

1. Department of Community Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia

2. Biostatistics and Research Methodology Unit, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia

3. Malaysian National Cancer Registry Department, National Cancer Institute, Ministry of Health Malaysia, Putrajaya 62250, Federal Territory of Putrajaya, Malaysia

4. Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia

5. Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia

6. Hospital Sibu, Ministry of Health Malaysia, Sibu 96000, Sarawak, Malaysia

7. Breast and Endocrine Surgery Unit, Department of Surgery, Hospital Raja Perempuan Zainab II, Ministry of Health Malaysia, Kota Bharu 15586, Kelantan, Malaysia

Abstract

Women with breast cancer are keen to know their predicted survival. We developed a new prognostic model for women with breast cancer in Malaysia. Using the model, this study aimed to design the user interface and develop the contents of a web-based prognostic tool for the care provider to convey survival estimates. We employed an iterative website development process which includes: (1) an initial development stage informed by reviewing existing tools and deliberation among breast surgeons and epidemiologists, (2) content validation and feedback by medical specialists, and (3) face validation and end-user feedback among medical officers. Several iterative prototypes were produced and improved based on the feedback. The experts (n = 8) highly agreed on the website content and predictors for survival with content validity indices ≥ 0.88. Users (n = 20) scored face validity indices of more than 0.90. They expressed favourable responses. The tool, named Malaysian Breast cancer Survival prognostic Tool (myBeST), is accessible online. The tool estimates an individualised five-year survival prediction probability. Accompanying contents were included to explain the tool’s aim, target user, and development process. The tool could act as an additional tool to provide evidence-based and personalised breast cancer outcomes.

Funder

School of Medical Sciences, Universiti Sains Malaysia

Publisher

MDPI AG

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference41 articles.

1. National Cancer Institute Ministry of Health (NCI MOH) Malaysia (2019). Malaysia National Cancer Registry Report 2012–2016.

2. Patient-Reported Outcome Measures among Breast Cancer Survivors: A Cross-Sectional Comparison between Malaysia and High-Income Countries;Rajaram;Psychooncology,2019

3. Mobile Health Application Applying the Health Belief Model for Breast Cancer Awareness: What Is Missing?;Nasution;Malays. J. Med. Health Sci.,2021

4. Prognostic Models for Breast Cancer: A Systematic Review;Phung;BMC Cancer,2019

5. Predicting Cancer Prognosis Using Interactive Online Tools: A Systematic Review and Implications for Cancer Care Providers;Rabin;Cancer Epidemiol. Biomark. Prev.,2013

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