Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder

Author:

Guleria Harsh Vardhan1,Luqmani Ali Mazhar1,Kothari Harsh Devendra1,Phukan Priyanshu1,Patil Shruti1ORCID,Pareek Preksha1,Kotecha Ketan1ORCID,Abraham Ajith2ORCID,Gabralla Lubna Abdelkareim3

Affiliation:

1. Symbiosis Institute of Technology, Symbiosis International University, Pune 412115, India

2. Faculty of Computing and Data Sciences, FLAME University, Lavale, Pune 412115, India

3. Department of Computer Science and Information Technology, College of Applied, Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia

Abstract

A breast tissue biopsy is performed to identify the nature of a tumour, as it can be either cancerous or benign. The first implementations involved the use of machine learning algorithms. Random Forest and Support Vector Machine (SVM) were used to classify the input histopathological images into whether they were cancerous or non-cancerous. The implementations continued to provide promising results, and then Artificial Neural Networks (ANNs) were applied for this purpose. We propose an approach for reconstructing the images using a Variational Autoencoder (VAE) and the Denoising Variational Autoencoder (DVAE) and then use a Convolutional Neural Network (CNN) model. Afterwards, we predicted whether the input image was cancerous or non-cancerous. Our implementation provides predictions with 73% accuracy, which is greater than the results produced by our custom-built CNN on our dataset. The proposed architecture will prove to be a new field of research and a new area to be explored in the field of computer vision using CNN and Generative Modelling since it incorporates reconstructions of the original input images and provides predictions on them thereafter.

Funder

Princess Nourah bint Abdulrahman University

Publisher

MDPI AG

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference50 articles.

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3. Cumula-tive advanced breast cancer risk prediction model developed in a screening mammography population;Kerlikowske;JNCI J. Natl. Cancer Inst.,2022

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5. Breast cancer prediction model with decision tree and adaptive boosting;Assegie;IAES Int. J. Artif. Intell. (IJ-AI),2021

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