Affiliation:
1. Department of Environmental Health Surveillance and Occupational Health, Health and Environmental Surveillance Secretariat, Ministry of Health (DSAST/SVSA/MS), SRTVN 701, Via W5 Norte, Brasilia 70719-040, Brazil
Abstract
Background: In this study, the annual leukemia mortality rate is estimated by occupational groups potentially exposed to benzene in Brazil and compared to non-exposed workers by sex. Methods: Data were extracted from the Mortality Information System and the National Institute of Geography and Statistics from 2006 to 2011. Occupational groups exposed to benzene were defined by using the Finnish Job-Exposure Matrix, FINJEM. Results: We found 21,049 leukemia deaths in 1917 in occupational groups potentially exposed to benzene, corresponding to an annual average mortality rate of 4.5/100,000, higher than the estimate for non-exposed workers: 2.6/100,000, corresponding to a Mortality rate ratio MRR = 1.7. Each benzene-exposed occupational group had increased leukemia mortality, and printers and occupations in graphics presented the highest MRR (2.7), followed by laboratory assistants (MRR = 2.6), laundry workers, chemists, and upholsterers, each of these occupational groups presenting MRR = 2.3. Conclusions: Benzene shows the need for better enforcement of protective norms against this known carcinogen. Our results support the need for better enforcement of protective norms to reduce benzene exposure.
Subject
Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health
Reference35 articles.
1. The Global Burden of Cancer 2013;Fitzmaurice;JAMA Oncol.,2015
2. Leukemia in benzene workers: A retrospective cohort study;Yin;Br. J. Ind. Med.,1987
3. An expanded cohort study of cancer among benzene-exposed workers in China. Benzene Study Group;Yin;Environ. Health Perspect.,1996
4. A retrospective cohort study of cause-specific mortality and incidence of hematopoietic malignancies in Chinese benzene-exposed workers;Linet;Int. J. Cancer,2015
5. Lymphatic and Hematopoietic Cancers Among Benzene-Exposed Workers;Collins;J. Occup. Environ. Med.,2015