Impact of Clinical Pharmacist Consultations on Postoperative Pain in Ambulatory Surgery

Author:

Barat Eric12ORCID,Chenailler Catherine1,Gillibert André3,Pouplin Sophie4,Varin Remi5,Compere Vincent6

Affiliation:

1. Department of Pharmacy, CHU Rouen, CEDEX, 76031 Rouen, France

2. Department of Pharmacy, Normandie University, UNICAEN, Inserm U1086, 14000 Caen, France

3. Department of Biostatistics, CHU Rouen, CEDEX, 76031 Rouen, France

4. Department of Rheumatology, CHU Rouen, CEDEX, 76031 Rouen, France

5. Department of Pharmacy, UNIROUEN, Inserm U1234, CHU Rouen, Normandie University, Rouen, CEDEX, 76031 Rouen, France

6. Department of Anesthesiology and Critical Care, CHU Rouen, CEDEX, 76031 Rouen, France

Abstract

Post-operative pain is a common symptom of ambulatory surgery. The objective of this study was to evaluate a pain management protocol integrating a pharmacist consultation. We conducted a quasi-experimental, single center, before-after study. The control group was recruited between 1 March and 31 May 2018 and the intervention group between 1 March and 31 May 2019. Outpatients in the intervention group received a pharmacist consultation, in addition to the usual anesthesiologist and nurse consultations. Pharmacist consultations were conducted in two steps: the first step consisted of general open-ended questions and the second step of a specific and individualized pharmaceutical interview. A total of 125 outpatients were included in each group. There were 17% (95% CI 5 to 27%, p = 0.022) fewer patients with moderate to severe pain in the pharmaceutical intervention group compared with the control group, which corresponded to a decrease in the mean pain level of 0.9/10 (95% CI −1.5/10; −0.3/10; p = 0.002). The multivariate analysis did not reveal any confounding factors, showing that only the pharmaceutical intervention could explain this result. This study demonstrates a positive impact of pharmacist consultations on postoperative pain in ambulatory surgery.

Funder

the Normandy Regional Health Agency

the Charles Nicolle Foundation

the Interregional Group for Clinical Research and Innovation of Northwest France

Publisher

MDPI AG

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference23 articles.

1. Postdischarge symptoms after ambulatory surgery: First-week incidence, intensity, and risk factors;Mattila;Anesth. Analg.,2005

2. Revision of expert panel’s guidelines on postoperative pain management;Aubrun;Anaesth. Crit. Care Pain. Med.,2019

3. NICE (2021, January 28). Managing Acute Postoperative Pain. Available online: https://www.nice.org.uk/guidance/ng180/evidence/n2-managing-acute-postoperative-pain-appendices-pdf-317993437914.

4. Chronic pain as an outcome of surgery. A review of predictive factors;Perkins;Anesthesiology,2000

5. Transition from acute to chronic pain after surgery;Glare;Lancet,2019

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