A Novel Low-Cost Uroflowmetry for Patient Telemonitoring

Author:

Pandolfo Savio Domenico12ORCID,Crauso Federica3,Aveta Achille1ORCID,Cilio Simone1ORCID,Barone Biagio1ORCID,Napolitano Luigi1,Scarpato Antonio1,Mirto Benito Fabio1,Serino Francesco4ORCID,Del Giudice Francesco56ORCID,Chung Benjamin I.6,Crocerossa Fabio7ORCID,Di Zazzo Erika8ORCID,Trama Francesco9,Vaglio Ruggero10,Wu Zhenjie11,Verze Paolo12,Imbimbo Ciro1,Crocetto Felice1ORCID

Affiliation:

1. Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples “Federico II”, 80131 Naples, Italy

2. Division of Urology, Virginia Commonwealth University (VCU) Health, Richmond, VA 23298, USA

3. Department of Public Health, University of Naples “Federico II”, 80125 Naples, Italy

4. NexsusTLC SRLS, 80010 Quarto, Italy

5. Department of Maternal-Infant and Urologic Sciences, “Sapienza” University of Rome, Policlinico Umberto I Hospital, 00161 Rome, Italy

6. Department of Urology, Stanford Medical Center, Stanford, CA 94305, USA

7. Urology Unit, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy

8. Department of Medicine and Health Sciences “V. Tiberio”, University of Molise, 86100 Campobasso, Italy

9. Andrological and Urogynecological Clinic, Santa Maria Terni Hospital, University of Perugia, 05100 Terni, Italy

10. Department of Physics, University of Naples “Federico II”, and CNR SPIN, 80125 Naples, Italy

11. Department of Urology, Changhai Hospital, Naval Medical University, Shanghai 200433, China

12. Department of Medicine and Surgery, Scuola Medica Salernitana, University of Salerno, 84081 Fisciano, Italy

Abstract

Uroflowmetry (UF) is a crucial guideline-recommended tool for men with benign prostatic obstruction (BPO). Moreover, UF is a helpful decision-making tool for the management of patients with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). In the last few years, telemedicine and telehealth have increased exponentially as cost-effective treatment options for both patients and physicians. Telemedicine and telehealth have been well positioned during the COVID-19 pandemic to prevent healthcare system overload and to ensure adequate management of patients through screening, diagnosis, and follow-up at home. In the present manuscript, the main characteristics and performance of a novel and low-cost device for home-based UF have been analyzed. The simple weight-transducer method has been applied to perform UF. An inexpensive load cell connected to a 24 bit analogic digital converter (ADC) sends data to a cloud server via SIM card or home Wi-Fi. Data are processed and shown in graphics with both volume and flow rate as a function of time, allowing for measurement of average flow rate, maximum flow rate, voided volume, and voiding time. A numerical algorithm allows for filtering of the dynamic effect due to the urine gravity acceleration and for removing the funnel to simplify the home measurement procedure. Through an online platform, the physician can see and compare each UF data. The device’s reliability has been validated in a first laboratory setting and showed excellent performance. This approach based on domiciliary tests and an online platform can revolutionize the urologic clinic landscape by offering a constant patient cost-effective follow-up, eliminating the time wasted waiting in the office setting.

Publisher

MDPI AG

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference27 articles.

1. (2022, September 30). EAU Guidelines on the Assessment of Non-Neurogenic Male Lower Urinary Tract Symptoms Including Benign Prostatic Obstruction, Available online: https://pubmed.ncbi.nlm.nih.gov/25613154/.

2. The fundamentals of uroflowmetry practice, based on International Continence Society good urodynamic practices recommendations;Gammie;Neurourol. Urodyn.,2018

3. Variability and circadian changes in home uroflowmetry in patients with benign prostatic hyperplasia compared to normal controls;Golomb;J. Urol.,1992

4. Methods and value of home uroflowmetry in the assessment of men with lower urinary tract symptoms: A literature review: Review of Home Uroflowmetry;Bray;Neurourol. Urodyn.,2012

5. The value of multiple free-flow studies in men with lower urinary tract symptoms;Reynard;Br. J. Urol.,1996

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