Abstract
Over time, large amounts of clinical data have accumulated in electronic health records (EHRs), making it difficult for healthcare professionals to navigate and make patient-centered decisions. This underscores the need for healthcare recommendation systems that help medical professionals make faster and more accurate decisions. This study addresses drug recommendation systems that generate an appropriate list of drugs that match patients’ diagnoses. Currently, recommendations are manually prepared by physicians, but this is difficult for patients with multiple comorbidities. We explored approaches to drug recommendations based on elderly patients with diabetes, hypertension, and cardiovascular disease who visited primary-care clinics and often had multiple conditions. We examined both collaborative filtering approaches and traditional machine-learning classifiers. The hybrid model between the two yielded a recall at 5 of 76.61%, a precision at 5 of 46.20%, a macro-averaged area under the curve of 74.52%, and an average physician agreement of 47.50%. Although collaborative filtering is widely used in recommendation systems, our results showed that it consistently underperformed traditional classification. Collaborative filtering was sensitive to class imbalances and favored the more popular classes. This study highlighted challenges that need to be addressed when developing recommendation systems in EHRs.
Subject
Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health
Reference25 articles.
1. Noncommunicable Diseases;Hunter;N. Engl. J. Med.,2013
2. GBD 2015 Risk Factors Collaborators (2016). Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: A systematic analysis for the Global Burden of Disease Study 2015. Lancet, 388, 1659–1724.
3. Diabetes, Hypertension, and Cardiovascular Disease;Sowers;Hypertension,2001
4. Non-communicable diseases in the Asia-Pacific region: Prevalence, risk factors and community-based prevention;Low;Int. J. Occup. Med. Environ. Health,2014
5. Hao, F., and Blair, R.H. (2016). A comparative study: Classification vs. user-based collaborative filtering for clinical prediction. BMC Med. Res. Methodol., 16.
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