(1R,2R,4R)-N-((4-((4-(2-Carboxyethyl)phenoxy)methyl)thiophen-2-yl)methyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-aminium Chloride-Reference-Cited by-同舟云学术

(1R,2R,4R)-N-((4-((4-(2-Carboxyethyl)phenoxy)methyl)thiophen-2-yl)methyl)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-aminium Chloride

Published:2023-04-07 Issue:2 Volume:2023 Page:M1617
ISSN:1422-8599
Container-title:Molbank
language:en
Short-container-title:Molbank

Author:

Kuranov Sergey O.¹,Marenina Mariya K.¹^ORCID,Khvostov Mikhail V.¹^ORCID,Luzina Olga A.¹^ORCID,Tolstikova Tatiana G.¹,Salakhutdinov Nariman F.¹

Affiliation:

1. N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9, Akademika Lavrentieva Ave., 630090 Novosibirsk, Russia

Abstract

A novel free fatty acid receptor 1 (FFAR1) agonist has been synthesized and evaluated in vitro. The synthesis of the title compound was performed from commercially available 4-hydroxybenzaldehyde, 2-thiophenecarboxaldehyde, and (+)-camphor. The compound was shown to have an affinity to FFAR1.

Funder

Russian Science Foundation

Publisher

MDPI AG

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://www.mdpi.com/1422-8599/2023/2/M1617/pdf

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