Diagnostic Accuracy of Lung Ultrasound in Neonatal Diseases: A Systematized Review

Author:

Nobile Stefano1ORCID,Sette Lucia1,Esposito Claudia2,Riitano Francesca1,Di Sipio Morgia Chiara1,Sbordone Annamaria1ORCID,Vento Giovanni1,Perri Alessandro1

Affiliation:

1. Neonatal Unit, Department of Mother, Child and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo F. Vito 1, 00168 Rome, Italy

2. Department of Woman, Child, General and Specialistic Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy

Abstract

Background: Respiratory problems are frequent in newborns, and are mainly studied with chest X-rays, whereas CT scans are usually needed for the evaluation of rare malformations and diseases. Lung ultrasound (LUS] has been proposed as an alternative method of diagnosing a variety of respiratory conditions. In recent years, there has been a rapid increase in LUS studies, thanks to the ability of LUS to rapidly exclude complications and significantly reduce radiation exposure in this fragile population. We aimed to summarize the current knowledge about LUS. Methods: A literature search was conducted on the Medline and Cochrane databases using appropriate terms. The inclusion criteria were: English language and human species. Exclusion criteria were: non-English language, animal species, case reports, case series, non-systematic reviews, and editorials. Results: The search returned 360 results. No Cochrane reviews were found. Titles and abstracts were screened, and 37 were finally considered. Studies concerning the use of lung ultrasound for the following conditions were presented: neonatal respiratory distress syndrome, transient tachypnea of the newborn, pneumothorax, pulmonary hemorrhage, pneumonia, bronchopulmonary dysplasia, and prediction of extubation success. Conclusions: We discussed the utility of LUS for the diagnosis and treatment of neonatal diseases according to the most recent literature.

Publisher

MDPI AG

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