Factors Associated with Defecation Satisfaction among Japanese Adults with Chronic Constipation

Author:

Yamamoto Sayuri12ORCID,Ohashi Wataru3,Yamaguchi Yoshiharu1,Igari Hiroki2,Koshino Akira1,Sugiyama Tomoya1,Nagao Kazuhiro1ORCID,Tamura Yasuhiro1,Izawa Shinya1,Mano Mamiko4,Ebi Masahide1ORCID,Usami Jun2,Hamano Koichi2,Izumi Junko2,Wakita Yoshinori2,Funaki Yasushi1,Ogasawara Naotaka1ORCID,Sasanabe Ryujiro4ORCID,Sasaki Makoto1,Maekawa Masato2,Kasugai Kunio1ORCID

Affiliation:

1. Division of Gastroenterology, Aichi Medical University, Nagakute 480-1195, Japan

2. Division of General Medicine, Aichi Medical University, Nagakute 480-1195, Japan

3. Division of Biostatistics, Clinical Research Center, Aichi Medical University, Nagakute 480-1195, Japan

4. Division of Sleep Medicine, Aichi Medical University, Nagakute 480-1195, Japan

Abstract

Background: Constipation causes substantial morbidity worldwide. Methods: This survey assessed constipation-related factors in Japan using the Japanese version of the Irritable Bowel Syndrome Quality of Life (IBS-QOL-J) instrument. We also examined the relationship among laxative type, Bristol Stool Form Scale (BSFS) scores, and treatment cost. Finally, we examined differences in satisfaction scores according to laxative type, treatment type, treatment cost, and BSFS score. Results: IBS-QOL-J was higher among those taking salt and/or irritation laxatives. Those paying >JPY 5000 (USD 50.00) had the lowest IBS-QOL-J. IBS-QOL-J was significantly lower among those with a BSFS score of 1 or 2 (severe constipation). Conclusions: This study’s findings suggest that a variety of factors, including treatment type and cost, are associated with defecation satisfaction. Those who had hard stools, used multiple laxatives, or spent more on treatment were less satisfied. Future strategies should target therapies that do not require multiple laxatives with lower treatment costs. Adequate defecation with a small number of appropriate laxatives at minimal cost appears to improve defecation satisfaction. It is desirable to identify appropriate laxatives and improve dietary habits and exercise routines. It is also necessary to stop blindly increasing laxative usage and properly diagnose constipation disorders such as anatomical abnormalities other than functional constipation.

Funder

EA Pharma Inc.

Publisher

MDPI AG

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