Utilizing Wearable Device Data for Syndromic Surveillance: A Fever Detection Approach

Author:

Kasl Patrick1ORCID,Keeler Bruce Lauryn2,Hartogensis Wendy3ORCID,Dasgupta Subhasis4,Pandya Leena S.3,Dilchert Stephan5ORCID,Hecht Frederick M.3,Gupta Amarnath46ORCID,Altintas Ilkay46,Mason Ashley E.3ORCID,Smarr Benjamin L.16ORCID

Affiliation:

1. Shu Chien-Gene Lay Department of Bioengineering, University of California San Diego, San Diego, CA 92093-0021, USA

2. UC San Diego Health Department of Biomedical Informatics, University of California San Diego, San Diego, CA 92093-0021, USA

3. UCSF Osher Center for Integrative Health, University of California San Francisco, San Francisco, CA 92093-0021, USA

4. San Diego Supercomputer Center, University of California San Diego, San Diego, CA 92093-0021, USA

5. Department of Management, Zicklin School of Business, Baruch College, The City University of New York, New York, NY 10010, USA

6. Halıcıoğlu Data Science Institute, University of California San Diego, San Diego, CA 92093-0021, USA

Abstract

Commercially available wearable devices (wearables) show promise for continuous physiological monitoring. Previous works have demonstrated that wearables can be used to detect the onset of acute infectious diseases, particularly those characterized by fever. We aimed to evaluate whether these devices could be used for the more general task of syndromic surveillance. We obtained wearable device data (Oura Ring) from 63,153 participants. We constructed a dataset using participants’ wearable device data and participants’ responses to daily online questionnaires. We included days from the participants if they (1) completed the questionnaire, (2) reported not experiencing fever and reported a self-collected body temperature below 38 °C (negative class), or reported experiencing fever and reported a self-collected body temperature at or above 38 °C (positive class), and (3) wore the wearable device the nights before and after that day. We used wearable device data (i.e., skin temperature, heart rate, and sleep) from the nights before and after participants’ fever day to train a tree-based classifier to detect self-reported fevers. We evaluated the performance of our model using a five-fold cross-validation scheme. Sixteen thousand, seven hundred, and ninety-four participants provided at least one valid ground truth day; there were a total of 724 fever days (positive class examples) from 463 participants and 342,430 non-fever days (negative class examples) from 16,687 participants. Our model exhibited an area under the receiver operating characteristic curve (AUROC) of 0.85 and an average precision (AP) of 0.25. At a sensitivity of 0.50, our calibrated model had a false positive rate of 0.8%. Our results suggest that it might be possible to leverage data from these devices at a public health level for live fever surveillance. Implementing these models could increase our ability to detect disease prevalence and spread in real-time during infectious disease outbreaks.

Funder

Department of Defense

#StartSmall foundation

Oura Health Oy

National Institutes of Health, USA

Publisher

MDPI AG

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