A Surface-Enhanced Raman Spectroscopy-Based Aptasensor for the Detection of Deoxynivalenol and T-2 Mycotoxins-Reference-Cited by-同舟云学术

A Surface-Enhanced Raman Spectroscopy-Based Aptasensor for the Detection of Deoxynivalenol and T-2 Mycotoxins

Published:2024-09-02 Issue:17 Volume:25 Page:9534
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Alieva Rugiya¹,Sokolova Svetlana¹,Zhemchuzhina Natalia²,Pankin Dmitrii³,Povolotckaia Anastasia³⁴^ORCID,Novikov Vasiliy⁴⁵^ORCID,Kuznetsov Sergey⁴⁵^ORCID,Gulyaev Anatoly⁴,Moskovskiy Maksim⁴^ORCID,Zavyalova Elena¹⁴

Affiliation:

1. Chemistry Department of Lomonosov Moscow State University, Moscow 119991, Russia

2. All-Russian Research Institute of Phytopathology, Bolshiye Vyazemy 143050, Russia

3. Center for Optical and Laser Materials Research, St. Petersburg State University, St. Petersburg 199034, Russia

4. Federal Scientific Agroengineering Center VIM, Moscow 109428, Russia

5. Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow 119991, Russia

Abstract

The quality of food is one of the emergent points worldwide. Many microorganisms produce toxins that are harmful for human and animal health. In particular, mycotoxins from Fusarium fungi are strictly controlled in cereals. Simple and robust biosensors are necessary for ‘in field’ control of the crops and processed products. Nucleic acid-based sensors (aptasensors) offer a new era of point-of-care devices with excellent stability and limits of detection for a variety of analytes. Here we report the development of a surface-enhanced Raman spectroscopy (SERS)-based aptasensor for the detection of T-2 and deoxynivalenol in wheat grains. The aptasensor was able to detect as low as 0.17% of pathogen fungi in the wheat grains. The portable devices, inexpensive SERS substrate, and short analysis time encourage further implementation of the aptasensors outside of highly equipped laboratories.

Funder

Ministry of Science and Higher Education of the Russian Federation for large scientific projects in priority areas of scientific and technological development

Publisher

MDPI AG

Link

https://www.mdpi.com/1422-0067/25/17/9534/pdf

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