A Computational Method to Assist the Diagnosis of Breast Disease Using Dynamic Thermography

Abstract

Breast cancer has been the second leading cause of cancer death among women. New techniques to enhance early diagnosis are very important to improve cure rates. This paper proposes and evaluates an image analysis method to automatically detect patients with breast benign and malignant changes (tumors). Such method explores the difference of Dynamic Infrared Thermography (DIT) patterns observed in patients’ skin. After obtaining the sequential DIT images of each patient, their temperature arrays are computed and new images in gray scale are generated. Then the regions of interest (ROIs) of those images are segmented and, from them, arrays of the ROI temperature are computed. Features are extracted from the arrays, such as the ones based on statistical, clustering, histogram comparison, fractal geometry, diversity indices and spatial statistics. Time series that are broken down into subsets of different cardinalities are generated from such features. Automatic feature selection methods are applied and used in the Support Vector Machine (SVM) classifier. In our tests, using a dataset of 68 images, 100% accuracy was achieved.