Impact on Glycemic Variation Caused by a Change in the Dietary Intake Sequence

Author:

Alonso-Bastida Alexis1ORCID,Adam-Medina Manuel1ORCID,Salazar-Piña Dolores-Azucena2ORCID,Escobar-Jiménez Ricardo-Fabricio1ORCID,Parra-Cabrera María-Socorro3,Cervantes-Bobadilla Marisol4ORCID

Affiliation:

1. TecNM/CENIDET, Electronic Engineering Department, Interior Internado Palmira S/N, Palmira, Cuernavaca 62490, Mexico

2. Faculty of Nutrition, UAEM, Cuernavaca 62350, Mexico

3. Population Health Research Center, National Institute of Public Health, Cuernavaca 62100, Mexico

4. Center of Research in Engineering and Applied Sciences (CIICAp-IICBA)/UAEM, Av. Universidad 1001, Chamilpa, Cuernavaca 62209, Mexico

Abstract

This work presents an analysis of the effect on glycemic variation caused by modifying the macronutrient intake sequence in a person without a diagnosis of diabetes. In this work, three types of nutritional studies were developed: (1) glucose variation under conditions of daily intake (food mixture); (2) glucose variation under conditions of daily intake modifying the macronutrient intake sequence; (3) glucose variation after a modification in the diet and macronutrient intake sequence. The focus of this research is to obtain preliminary results on the effectiveness of a nutritional intervention based on the modification of the sequence of macronutrient intake in a healthy person during 14-day periods. The results obtained corroborate the positive effect on the glucose of consuming vegetables, fiber, or proteins before carbohydrates, decreasing the peaks in the postprandial glucose curves (vegetables: 113–117 mg/dL; proteins: 107–112 mg/dL; carbohydrates: 115–125 mg/dL) and reducing the average levels of blood glucose concentrations (vegetables: 87–95 mg/dL; proteins: 82–99 mg/dL; carbohydrates: 90–98 mg/dL). The present work demonstrates the preliminary potential of the sequence in the macronutrient intake for the generation of alternatives of prevention and solution of chronic degenerative diseases, improving the management of glucose in the organism and permeating in the reduction of weight and the state of health of the individuals.

Funder

Consejo Nacional de Ciencia y Tecnología of Mexico

Tecnológico Nacional de México

Publisher

MDPI AG

Subject

Plant Science,Health Professions (miscellaneous),Health (social science),Microbiology,Food Science

Reference36 articles.

1. World Health Organization (2023, February 23). Healthy Diet. Available online: www.who.int/news-room/fact-sheets/detail/healthy-diet.

2. Assessing the Shape of the Glucose Curve During an Oral Glucose Tolerance Test;Tschritter;Diabetes Care,2003

3. Food intake sequence modulates postprandial glycemia;Soeters;Clin. Nutr.,2020

4. Glycemic variability in the development of cardiovascular complications in diabetes;Nusca;Diabetes Metab. Res. Rev.,2018

5. Reducing postprandial glucose in dietary intervention studies and the magnitude of the effect on diabetes-related risk factors: A systematic review and meta-analysis;Ruijgrok;Eur. J. Nutr.,2021

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