Rheumatoid Arthritis from Easy to Complex Disease: From the “2022 GISEA International Symposium”

Author:

Perniola Simone12ORCID,Chimenti Maria3ORCID,Spinelli Francesca4ORCID,Frediani Bruno5,Foti Rosario6,Ferrigno Sara3,Garufi Cristina4,Cassone Giulia7ORCID,Venerito Vincenzo8ORCID,Atzeni Fabiola9,Caporali Roberto10,Conti Fabrizio4,Favalli Ennio1011,Iannone Florenzo8ORCID,Sebastiani Marco7ORCID,Ferraccioli Gian1,Lapadula Giovanni8ORCID,Gremese Elisa12

Affiliation:

1. Immunology Research Core Facility, Gemelli Science and Technology Park (GSTeP), Fondazione Policlinico Universitario A. Gemelli IRCCS—Rome, 00168 Rome, Italy

2. Division of Clinical Immunology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore—Rome, 00168 Rome, Italy

3. Rheumatology, Allergology and Clinical Immunology, Department of “Medicina dei Sistemi”, University of Rome Tor Vergata, 00133 Rome, Italy

4. Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari-Reumatologia, Sapienza Università di Roma, 00185 Rome, Italy

5. Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy

6. Rheumatology Unit, San Marco Hospital, Policlinico University of Catania, 95124 Catania, Italy

7. Rheumatology Unit, Azienda Ospedaliera Policlinico di Modena, University of Modena and Reggio Emilia, 41121 Modena, Italy

8. Department of Emergency and Organ Transplantation, Rheumatology Unit, University of Bari, 70121 Bari, Italy

9. Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, 98122 Messina, Italy

10. Department of Rheumatology and Clinical Sciences, ASST Gaetano Pini-CTO, 20126 Milan, Italy

11. Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy

Abstract

Rheumatoid Arthritis (RA) is a systemic disease with many different clinical phenotypes. RA could be classified according to disease duration, seropositivity for rheumatoid factor (RF) and/or anti-citrullinated protein antibodies (ACPA), joint subtype, clinical behaviourbehavior and many other subgroups. In this review, we summarize and discuss the multifaceted aspects of RA, focusing on the relationship between autoimmunity status and clinical outcome, achievement of remission and influence on treatment response, from the 2022 International GISEA/OEG Symposium.

Publisher

MDPI AG

Subject

General Medicine

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