Machine Learning Assisted Wearable Wireless Device for Sleep Apnea Syndrome Diagnosis

Author:

Wang Shaokui1,Xuan Weipeng1ORCID,Chen Ding1,Gu Yexin1,Liu Fuhai1,Chen Jinkai1ORCID,Xia Shudong2,Dong Shurong3ORCID,Luo Jikui13ORCID

Affiliation:

1. Ministry of Education Key Laboratory of RF Circuits and Systems, College of Electronics & Information Hangzhou Dianzi University, Hangzhou 310018, China

2. The Fourth Affiliated Hospital Zhejiang University School of Medicine, Yiwu 322000, China

3. Key Laboratory of Advanced Micro/Nano Electronic Devices & Smart Systems of Zhejiang, College of Information Science & Electronic Engineering, Zhejiang University, Hangzhou 310027, China

Abstract

Sleep apnea syndrome (SAS) is a common but underdiagnosed health problem related to impaired quality of life and increased cardiovascular risk. In order to solve the problem of complicated and expensive operation procedures for clinical diagnosis of sleep apnea, here we propose a small and low-cost wearable apnea diagnostic system. The system uses a photoplethysmography (PPG) optical sensor to collect human pulse wave signals and blood oxygen saturation synchronously. Then multiscale entropy and random forest algorithms are used to process the PPG signal for analysis and diagnosis of sleep apnea. The SAS determination is based on the comprehensive diagnosis of the PPG signal and blood oxygen saturation signal, and the blood oxygen is used to exclude the error induced by non-pathological factors. The performance of the system is compared with the Compumedics Grael PSG (Polysomnography) sleep monitoring system. This simple diagnostic system provides a feasible technical solution for portable and low-cost screening and diagnosis of SAS patients with a high accuracy of over 85%.

Funder

National Natural Science Foundation of China

Zhejiang Province Key R & D programs

NSFC-Zhejiang Joint Fund for the Integration of Industrialization and information

Publisher

MDPI AG

Subject

Clinical Biochemistry,General Medicine,Analytical Chemistry,Biotechnology,Instrumentation,Biomedical Engineering,Engineering (miscellaneous)

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