Contrast-Enhanced Mammography-Guided Biopsy: Preliminary Results of a Single-Center Retrospective Experience

Author:

Sammarra Matteo1,Piccolo Claudia Lucia1,Sarli Marina1,Stefanucci Rita1,Tommasiello Manuela1,Orsaria Paolo2,Altomare Vittorio3,Beomonte Zobel Bruno14ORCID

Affiliation:

1. Department of Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy

2. Department of Breast Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy

3. Department of Breast Surgery, Campus Bio-Medico University, 00128 Rome, Italy

4. Research Unit of Radiology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21, 00128 Rome, Italy

Abstract

Background: CEM-guided breast biopsy is an advanced diagnostic procedure that takes advantage of the ability of CEM to enhance suspicious breast lesions. The aim pf this paper is to describe a single-center retrospective experience on CEM-guided breast biopsy in terms of procedural features and histological outcomes. Methods: 69 patients underwent the procedure. Patient age, breast density, presentation, dimensions, and lesion target enhancement were recorded. All the biopsy procedures were performed using a 7- or 10-gauge (G) vacuum-assisted biopsy needle. The procedural approach (horizontal or vertical) and the decubitus of the patient (lateral or in a sitting position) were noted. Results: A total of 69 patients underwent a CEM-guided biopsy. Suspicious lesions presented as mass enhancement in 35% of cases and non-mass enhancement in 65% of cases. The median size of the target lesions was 20 mm. The median procedural time for each biopsy was 10 ± 4 min. The patients were placed in a lateral decubitus position in 52% of cases and seated in 48% of cases. The most common approach was horizontal (57%). The mean AGD was 14.8 mGy. At histology, cancer detection rate was 28% (20/71). Conclusions: CEM-guided biopsy was feasible, with high procedure success rates and high tolerance by the patients.

Publisher

MDPI AG

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