A Review of the Production of Hyaluronic Acid in the Context of Its Integration into GBAER-Type Biorefineries

Author:

Pérez-Morales Guadalupe1ORCID,Poggi-Varaldo Héctor Mario1,Ponce-Noyola Teresa2,Pérez-Valdespino Abigail3ORCID,Curiel-Quesada Everardo3ORCID,Galíndez-Mayer Juvencio4ORCID,Ruiz-Ordaz Nora4,Sotelo-Navarro Perla Xochitl5ORCID

Affiliation:

1. Environmental Biotechnology and Renewable Energies R&D Group, Department of Biotechnology and Bioengineering, Centro de Investigación y de Estudios Avanzados del IPN, P.O. Box 14-740, Mexico City 07000, Mexico

2. Microbial Genetics Group, Department of Biotechnology and Bioengineering, Centro de Investigación y de Estudios Avanzados del IPN, P.O. Box 14-740, Mexico City 07000, Mexico

3. Departamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 11350, Mexico

4. Departamento de Ingeniería Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City 07738, Mexico

5. Departamento de Energía, Área de Tecnologías Sustentables, Universidad Autónoma Metropolitana, Mexico City 02200, Mexico

Abstract

Biorefineries (BRFs) that process the organic fraction of municipal solid waste and generate bioproducts and bioenergies have attracted attention because they can simultaneously address energy and environmental problems/needs. The objective of this article was to critically review the microbial production of hyaluronic acid (MPHA) and its production profile for its integration into a GBAER-type BRF (a type of BRF based on organic wastes) and to identify the environmental and economic sustainability aspects of the modified BRF that would confirm it as a sustainable option. It was found that the MPHA by selected strains of pathogenic Streptococci was moderate to high, although the trend to work with genetically transformed (GT) (innocuous) bacteria is gaining momentum. For instance, A GT strain of Corynebacterium glutamicum reached a maximum HA production of 71.4 g L−1. MPHA reports that use organic wastes as sources of carbon (C) and nitrogen (N) are scarce. When alternative sources of C and N were used simultaneously, HA production by S. zooepidemicus was lower than that with conventional sources. We identified several knowledge gaps that must be addressed regarding aspects of process scale-up, HA industrial production, economic feasibility and sustainability, and environmental sustainability of the MPHA.

Publisher

MDPI AG

Reference155 articles.

1. Consolidation of Management Practices for Sustainable Product Development: A Systematic Literature Review;Vilochani;Sustain. Prod. Consum.,2024

2. Gawel, E., Pannicke, N., and Hagemann, N. (2019). A Path Transition towards a Bioeconomy-The Crucial Role of Sustainability. Sustainability, 11.

3. Valorisation of Agro-Industrial Wastes: Circular Bioeconomy and Biorefinery Process–A Sustainable Symphony;Wagh;Process Saf. Environ. Prot.,2024

4. Energy Institute (2024, January 08). Oil Reserves, 1980 to 2020. Available online: https://ourworldindata.org/grapher/oil-proved-reserves?tab=chart.

5. IPCC (2022). Summary for Policymakers: Climate Change 2022–Impacts, Adaptation and Vulnerability_Working Group II Contribution to the Sixth Assessment Report of the Intergovernamental Panel on Climate Change, Cambridge University Press.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3