Emerging Trends in Nanotechnology for Endometriosis: Diagnosis to Therapy

Author:

Talukdar Souvanik1,Singh Santosh K.1ORCID,Mishra Manoj K.2ORCID,Singh Rajesh13ORCID

Affiliation:

1. Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA

2. Cancer Biology Research and Training, Department of Biological Sciences, Alabama State University, Montgomery, AL 36104, USA

3. Cancer Health Equity Institute, Morehouse School of Medicine, Atlanta, GA 30310, USA

Abstract

Endometriosis, an incurable gynecological disease that causes abnormal growth of uterine-like tissue outside the uterine cavity, leads to pelvic pain and infertility in millions of individuals. Endometriosis can be treated with medicine and surgery, but recurrence and comorbidities impair quality of life. In recent years, nanoparticle (NP)-based therapy has drawn global attention, notably in medicine. Studies have shown that NPs could revolutionize conventional therapeutics and imaging. Researchers aim to enhance the prognosis of endometriosis patients with less invasive and more effective NP-based treatments. This study evaluates this potential paradigm shift in endometriosis management, exploring NP-based systems for improved treatments and diagnostics. Insights into nanotechnology applications, including gene therapy, photothermal therapy, immunotherapy, and magnetic hyperthermia, offering a theoretical reference for the clinical use of nanotechnology in endometriosis treatment, are discussed in this review.

Funder

National Institutes of Health

National Cancer Institute

American Cancer Society

Department of Defense

Publisher

MDPI AG

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