Author:
Vasey Clayton,McBride Jennifer,Penta Kayla
Abstract
Sleep is an essential component of overall human health but is so tightly regulated that when disrupted can cause or worsen certain ailments. An important part of this process is the presence of the well-known hormone, melatonin. This compound assists in the governing of sleep and circadian rhythms. Previous studies have postulated that dysregulation of melatonin rhythms is the driving force behind sleep and circadian disorders. A computer-aided search spanning the years of 2015–2020 using the search terms melatonin, circadian rhythm, disorder yielded 52 full text articles that were analyzed. We explored the mechanisms behind melatonin dysregulation and how it affects various disorders. Additionally, we examined associated therapeutic treatments including bright light therapy (BLT) and exogenous forms of melatonin. We found that over the past 5 years, melatonin has not been widely investigated in clinical studies thus there remains large gaps in its potential utilization as a therapy.
Subject
Food Science,Nutrition and Dietetics
Reference93 articles.
1. Reviewers and Writers What Is Sleep and Why Is It Important?,2016
2. https://www.sleepassociation.org/about-sleep/how-important-is-sleep/
3. New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation
4. Adenosine and Sleep
5. Serotonin: a review
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