Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

Abstract

Nonsteroidal anti-inflammatory medications (NSAIDs) are commonly used painkillers, anti-inflammatory agents, and fever reducers. They arrive in the environment from municipal wastewater and/or agriculture waste, affecting growing plants. In our study, the impact of NSAIDs, namely, diclofenac, indomethacin, naproxen, and paracetamol, on four plant species from the Fabaceae family (Cicer arietinum, Pisum sativum, Lens culinaris, and Vicia faba) was tested. The assimilation rate and stomatal conductance decreased for all plants treated with NSAIDs. Chlorophyll and carotenoid contents in the leaves of plants under stress declined by more than 15% compared with the control plants, while the flavonoids and total phenols decreased to a lesser extent. In contrast, the plants treated with NSAIDs emit terpenes and green leaf were volatile, at a level of some nmol m−2 s−1, which could influence the atmospheric reaction and ozone formation.