Composite Angioimmunoblastic T-Cell Lymphoma and Diffuse Large B-Cell Lymphoma Presenting with Distributive Shock-Reference-Cited by-同舟云学术

Composite Angioimmunoblastic T-Cell Lymphoma and Diffuse Large B-Cell Lymphoma Presenting with Distributive Shock

Published:2023-11-16 Issue:4 Volume:15 Page:627-633
ISSN:2038-8330
Container-title:Hematology Reports
language:en
Short-container-title:Hematology Reports

Author:

Hariharan Nisha¹,Kabadi Alisha²,Don Michelle³,Odish Mazen²,Heyman Benjamin⁴^ORCID

Affiliation:

1. Department of Medicine, Division of Hematology/Oncology, University of California, La Jolla, CA 92093, USA

2. Department of Medicine, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, University of California, La Jolla, CA 92093, USA

3. Department of Pathology, University of California, La Jolla, CA 92093, USA

4. Department of Medicine, Division of Regenerative Medicine, University of California, La Jolla, CA 92093, USA

Abstract

Diffuse large B-cell lymphoma (DLBCL) and angioimmunoblastic T-cell lymphoma (AITL) are two subtypes of non-Hodgkin lymphoma (NHL). The simultaneous occurrence of DLBCL and AITL in a composite lymphoma is very rare, and there are no established treatment regimens. We present the case of an 85-year-old male admitted to the intensive care unit with distributive shock, lymphocytosis, and lymphadenopathy, who was subsequently diagnosed with composite AITL and DLBCL, and treated with brentuximab vedotin (BV) and rituximab. To our knowledge, this is the first case of composite lymphoma presenting with distributive shock and treated with BV and rituximab, with successful resolution of shock.

Publisher

MDPI AG

Subject

Hematology

Link

https://www.mdpi.com/2038-8330/15/4/64/pdf

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