Cellular Processes Induced by HSV-1 Infections in Vestibular Neuritis

Author:

Zhao Zhengdong1,Liu Xiaozhou1,Zong Yanjun1,Shi Xinyu1,Sun Yu12ORCID

Affiliation:

1. Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China

2. Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan 430022, China

Abstract

Herpesvirus is a prevalent pathogen that primarily infects human epithelial cells and has the ability to reside in neurons. In the field of otolaryngology, herpesvirus infection primarily leads to hearing loss and vestibular neuritis and is considered the primary hypothesis regarding the pathogenesis of vestibular neuritis. In this review, we provide a summary of the effects of the herpes virus on cellular processes in both host cells and immune cells, with a focus on HSV-1 as illustrative examples.

Funder

the Innovative Research Groups of Hubei Province

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

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