Global Measles Surveillance: Trends, Challenges, and Implications for Public Health Interventions

Author:

Branda Francesco1ORCID,Giovanetti Marta234ORCID,Romano Chiara1,Benvenuto Domenico5ORCID,Ciccozzi Alessandra6,Sanna Daria6ORCID,Ciccozzi Massimo1ORCID,Scarpa Fabio6ORCID

Affiliation:

1. Unit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy

2. Department of Sciences and Technologies for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, 00128 Rome, Italy

3. Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Belo Horizonte 30.190-009, Brazil

4. Climate Amplified Diseases and Epidemics (CLIMADE), Brazil

5. Medical Statistic and Molecular Epidemiology Unit, Universita Cattolica di Roma, 00135 Rome, Italy

6. Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy

Abstract

Measles, a highly contagious disease primarily affecting children, carries serious health risks, including complications and mortality. Vaccination remains the most effective preventive measure against measles transmission. The COVID-19 pandemic has exacerbated challenges in surveillance and immunization efforts, leaving millions of people exposed to preventable diseases such as measles. Globally accelerated immunization campaigns are critical for achieving regional elimination goals and mitigating the risk of outbreaks. Our team has developed an open-access database for global measles monitoring, facilitating standardized data collection and analysis. The analysis of measles cases from 2011 to 2023 reveals fluctuating trends, with notable increases in Africa in 2019 and 2023, indicating potential gaps in control strategies. Using an automated signal detection tool developed by the European Centre for Disease Prevention and Control (ECDC) team, we identified significant variations between World Health Organization (WHO) regions, underscoring the importance of continuous monitoring to detect epidemiological changes early. These results underscore the need for robust surveillance systems and accelerated vaccination efforts to safeguard public health.

Publisher

MDPI AG

Reference19 articles.

1. Atkinson, W. (2006). Epidemiology and Prevention of Vaccine-Preventable Diseases, Department of Health & Human Services, Centers for Disease Control and Prevention.

2. The basic reproduction number (R0) of measles: A systematic review;Guerra;Lancet Infect. Dis.,2017

3. World Health Organization (2024, February 12). Measles Fact Sheet N°286. Available online: https://web.archive.org/web/20150203144905/http:/www.who.int/mediacentre/factsheets/fs286/en/.

4. Bope, E.T., and Kellerman, R.D. (2014). Conn’s Current Therapy 2015, Elsevier Health Sciences.

5. Oncolytic measles virotherapy and opposition to measles vaccination;Russell;Mayo Clin. Proc.,2019

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