Emerging Transcatheter Therapies for Valvular Heart Disease: Focus on Mitral and Tricuspid Valve Procedures

Author:

Ktenopoulos Nikolaos1ORCID,Katsaros Odysseas1ORCID,Apostolos Anastasios1ORCID,Drakopoulou Maria1,Tsigkas Grigorios2ORCID,Tsioufis Constantinos1,Davlouros Periklis2,Toutouzas Konstantinos1,Karanasos Antonios2ORCID

Affiliation:

1. First Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, 11527 Athens, Greece

2. Department of Cardiology, Patras University Hospital, 26504 Patras, Greece

Abstract

The emergence of percutaneous treatment options provides novel therapeutic alternatives for older and feeble patients who are at high risk for any surgical procedure. The purpose of our review was to offer an up-to-date analysis of the rapidly expanding field of percutaneous technologies for mitral, tricuspid, and pulmonary procedures. Edge-to-edge repair is an established treatment for secondary mitral regurgitation (MR), while transcatheter mitral valve replacement is a potential and expanding option for managing both secondary and primary MR. However, additional advancements are necessary to enhance the safety and feasibility of this procedure. Transcatheter tricuspid intervention is an emerging option that was conceived after the success of transcatheter procedures in aortic and mitral valves, and it is currently still in the early stages of advancement. This can be attributed, at least in part, to the previously overlooked effect of tricuspid regurgitation on patient outcomes. The development of edge-to-edge repair represents the forefront of innovations in transcatheter procedures. There is a scarcity of data about tricuspid annuloplasty and replacement, and further study is necessary. Transcatheter mitral, tricuspid, and pulmonary procedures show prospects for the future, while their role in clinical practice has not been definitively established.

Funder

This paper has been financed by the funding program “MEDICUS”, of the University of Patras

Publisher

MDPI AG

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