A High Grade Astrocytoma with Pilocytic Morphology in a 5-Month-Old American Bulldog

Abstract

A 23-week-old female intact American Bulldog was presented for a two-week history of progressive circling to the right, twitching, and altered mentation. Magnetic resonance imaging (MRI) revealed a non-contrast enhancing hemorrhagic mass centered in the right thalamus with concurrent subdural and intraventricular hemorrhage. Post-mortem histologic examination of the brain confirmed a mass centered on the thalamus with histomorphologic features consistent with a high-grade astrocytoma with pilocytic morphology. To the authors’ knowledge, the present case is the first to report clinical and imaging characteristics of a high-grade astrocytoma with pilocytic morphology in a young dog.