The Dictyostelium Centrosome

Author:

Gräf RalphORCID,Grafe Marianne,Meyer Irene,Mitic Kristina,Pitzen Valentin

Abstract

The centrosome of Dictyostelium amoebae contains no centrioles and consists of a cylindrical layered core structure surrounded by a corona harboring microtubule-nucleating γ-tubulin complexes. It is the major centrosomal model beyond animals and yeasts. Proteomics, protein interaction studies by BioID and superresolution microscopy methods led to considerable progress in our understanding of the composition, structure and function of this centrosome type. We discuss all currently known components of the Dictyostelium centrosome in comparison to other centrosomes of animals and yeasts.

Funder

Deutsche Forschungsgemeinschaft

Publisher

MDPI AG

Subject

General Medicine

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