A Systematic Review of New Imaging Technologies for Robotic Prostatectomy: From Molecular Imaging to Augmented Reality

Author:

Rodler Severin1ORCID,Kidess Marc Anwar1,Westhofen Thilo1,Kowalewski Karl-Friedrich2,Belenchon Ines Rivero3ORCID,Taratkin Mark4,Puliatti Stefano5ORCID,Gómez Rivas Juan6ORCID,Veccia Alessandro7ORCID,Piazza Pietro8ORCID,Checcucci Enrico9ORCID,Stief Christian Georg1,Cacciamani Giovanni Enrico10ORCID

Affiliation:

1. Department of Urology, University Hospital of Munich, 81377 Munich, Germany

2. Department of Urology, Klinikum Mannheim, 68167 Mannheim, Germany

3. Urology and Nephrology Department, Virgen del Rocío University Hospital, Manuel Siurot s/n, 41013 Seville, Spain

4. Institute for Urology and Reproductive Health, Sechenov University, 117418 Moscow, Russia

5. Department of Urology, University of Modena and Reggio Emilia, 42122 Modena, Italy

6. Department of Urology, Hospital Clinico San Carlos, 28040 Madrid, Spain

7. Urology Unit, Azienda Ospedaliera Universitaria Integrata Verona, 37126 Verona, Italy

8. Division of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy

9. Department of Surgery, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, 10060 Turin, Italy

10. USC Institute of Urology, University of Southern California, Los Angeles, CA 90007, USA

Abstract

New imaging technologies play a pivotal role in the current management of patients with prostate cancer. Robotic assisted radical prostatectomy (RARP) is a standard of care for localized disease and through the already imaging-based console subject of research towards combinations of imaging technologies and RARP as well as their impact on surgical outcomes. Therefore, we aimed to provide a comprehensive analysis of the currently available literature for new imaging technologies for RARP. On 24 January 2023, we performed a systematic review of the current literature on Pubmed, Scopus and Web of Science according to the PRISMA guidelines and Oxford levels of evidence. A total of 46 studies were identified of which 19 studies focus on imaging of the primary tumor, 12 studies on the intraoperative tumor detection of lymph nodes and 15 studies on the training of surgeons. While the feasibility of combined approaches using new imaging technologies including MRI, PSMA-PET CT or intraoperatively applied radioactive and fluorescent dyes has been demonstrated, the prospective confirmation of improvements in surgical outcomes is currently ongoing.

Publisher

MDPI AG

Subject

General Medicine

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