Long-Term Outcomes of Birdshot Chorioretinopathy Treated with Corticosteroids: A Case Reports

Author:

Ferracci Dino1,Mathis Thibaud12ORCID,Gavoille Antoine3,Gerfaud-Valentin Mathieu4ORCID,Bert Arthur4,Hafidi Meriem1,Denis Philippe1,Loria Olivier12,Kodjikian Laurent12ORCID,Sève Pascal456ORCID

Affiliation:

1. Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, 69004 Lyon, France

2. UMR5510 MATEIS, CNRS, INSA Lyon, Université Lyon 1, 69100 Villeurbanne, France

3. Department of Biostatistics-Bioinformatics, Hospices Civils de Lyon, 69007 Lyon, France

4. Department of Internal Medicine, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, 69004 Lyon, France

5. Hospices Civils de Lyon, Pôle IMER, 69003 Lyon, France

6. University Lyon, University Claude Bernard-Lyon 1, HESPER EA 7425, 69008 Lyon, France

Abstract

Purpose: To report the progression of patients diagnosed with birdshot chorioretinopathy (BSCR) initially treated with corticosteroids. Methods: We included 39 BSCR patients that were followed for ≥1 year. We analyzed their progression under treatment after 1, 3, 6 months, 1 year, and at the end of follow-up. In order to determine the efficiency of initial loading doses, patients were classified into two groups according to their initial treatment: methylprednisolone followed by prednisone (n = 28) and prednisone alone (n = 11). Results: At the end of follow-up, 31/39 (79.5%) patients had reached inflammation control. Thirteen out of 28 (46.4%) and 6/11 (54.5%) patients were treated exclusively with corticosteroids, and 18/19 (94.7%) of them had reached inflammation control at the end of follow-up; their mean (range) corticosteroid dose was 3.5 (0–10) mg/day. Conclusions: We found that the prolonged corticosteroid therapy treatment strategy resulted in inflammation control in half of BSCR patients. This control was maintained with low doses of cortisone, usually <5 mg/day.

Publisher

MDPI AG

Subject

General Medicine

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