Affiliation:
1. Department of Chemistry, College of William and Mary, Williamsburg, VA 23185, USA
Abstract
Dynamic range is a crucial aspect in the development of fluorescent chemosensors. We aimed to address this issue using molecular logic gates. By creating an AND logic gate with two binding sites for the same type of ion, we increased the dynamic range of a sodium chemosensor while still using the same ionophore. Naphthalimide derivatives 1 and 2 were synthesized to test the plausibility of this application. Being an AND logic gate, the second molecule requires two Na+ ions, while molecule 1 requires a single ion for sensing. The application of this molecular logic gate is a useful method of altering the chemosensor range.
Reference34 articles.
1. Fluorescent Chemosensors: The Past, Present and Future;Wu;Chem. Soc. Rev.,2017
2. Desvergne, J.P., and Czarnik, A.W. (1993). Fluorescent Chemosensors for Ion and Molecule Recognition, American Chemical Society.
3. Fluorescent probes for disease diagnosis;Wang;Chem. Rev.,2024
4. Recent advances in colorimetric and fluorescent chemosensors for Ionic species: Design, principle and optical signalling mechanism;Dongare;ChemistrySelect,2021
5. Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes;Li;Chem. Rev.,2014