Recent Development of Rhenium-Based Materials in the Application of Diagnosis and Tumor Therapy-Reference-Cited by-同舟云学术

Recent Development of Rhenium-Based Materials in the Application of Diagnosis and Tumor Therapy

Published:2023-03-17 Issue:6 Volume:28 Page:2733
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Qi Qingwen¹,Wang Qian¹,Li Yuhao¹²^ORCID,Silva Dionisio Zaldivar²³^ORCID,Ruiz Maria Eliana Lanio²³,Ouyang Ruizhuo¹²^ORCID,Liu Baolin²⁴,Miao Yuqing¹²

Affiliation:

1. School of Materials and Chemistry, Institute of Bismuth and Rhenium, University of Shanghai for Science and Technology, Shanghai 200093, China

2. USST-UH International Joint Laboratory for Tumor Diagnosis and Energy Treatment, University of Shanghai for Science and Technology, Shanghai 200093, China

3. Faculty of Biology, University of Havana, Havana 10400, Cuba

4. School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China

Abstract

Rhenium (Re) is widely used in the diagnosis and treatment of cancer due to its unique physical and chemical properties. Re has more valence electrons in its outer shell, allowing it to exist in a variety of oxidation states and to form different geometric configurations with many different ligands. The luminescence properties, lipophilicity, and cytotoxicity of complexes can be adjusted by changing the ligand of Re. This article mainly reviews the development of radionuclide 188Re in radiotherapy and some innovative applications of Re as well as the different therapeutic approaches and imaging techniques used in cancer therapy. In addition, the current application and future challenges and opportunities of Re are also discussed.

Funder

the Natural Science Foundation of Shanghai

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/28/6/2733/pdf

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