Synthesis, Docking Studies and Biological Evaluation of Benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one Derivatives on 5-HT1A Serotonin Receptors-Reference-Cited by-同舟云学术

Synthesis, Docking Studies and Biological Evaluation of Benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one Derivatives on 5-HT1A Serotonin Receptors

Published:2012-02-03 Issue:2 Volume:17 Page:1388-1407
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Pessoa-Mahana Hernán,Recabarren-Gajardo Gonzalo,Temer Jenny Fiedler,Zapata-Torres Gerald,Pessoa-Mahana C. David,Barría Claudio Saitz,Araya-Maturana Ramiro

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

http://www.mdpi.com/1420-3049/17/2/1388/pdf

Reference35 articles.

1. Derivatives as 5HT1A Receptor Ligands-Past and Present

2. Central monoamines and their role in major depression

3. Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl-and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity;Czopek;Eur. J. Med. Chem.,2010

4. Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity, Part 1

5. 5-HT(1A) receptor function in major depressive disorder;Savitz;Prog. Neurobiol.,2009

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