Author:
Lipilin Dmitry L.,Frumkin Alexander E.,Tyurin Alexey Y.,Levin Vitalij V.,Dilman Alexander D.
Abstract
A reaction of aromatic halides bearing electron-withdrawing groups with tertiary amines in the presence of an iridium catalyst under blue light irradiation is described. Products of the aromatic substitution of the halide by the dialkylamino fragment are obtained. The interaction of aryl radicals with tertiary amines to generate zwitterionic radical species is believed to be the key factor responsible for the reaction efficiency.
Funder
Zelinsky Institute of organic chemistry
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Reference55 articles.
1. Modern Nucleophilic Aromatic Substitution;Terrier,2013
2. Nucleophilic aromatic substitution;Caron,2020
3. Perfluoroheteroaromatic chemistry: Multifunctional systems from perfluorinated heterocycles by nucleophilic aromatic substitution processes;Sandford;Top. Heterocycl. Chem.,2012
4. Fluorination of aromatic compounds by halogen exchange with fluoride anions (‘‘halex’’ reaction);Langlois,1996
5. Transition Metal Catalyzed Synthesis of Arylamines and Aryl Ethers from Aryl Halides and Triflates: Scope and Mechanism
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献