Iridium-Catalysed Transfer Hydrogenation of 1,8-Naphthyridine with Indoline: Access to Functionalized N-Heteroarenes-Reference-Cited by-同舟云学术

Iridium-Catalysed Transfer Hydrogenation of 1,8-Naphthyridine with Indoline: Access to Functionalized N-Heteroarenes

Published:2023-12-01 Issue:23 Volume:28 Page:7886
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Zhou Changjian¹^ORCID,Zhang Jiahao¹,Fu Yuqing¹,Chen Chunlian²,Zhao He¹

Affiliation:

1. School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China

2. Key Lab of Functional Molecular Engineering of Guangdong Province, School of Chemistry & Chemical Engineering, South China University of Technology, Guangzhou 510640, China

Abstract

An iridium-catalysed hydrogen transfer strategy, enabling straightforward access to tetrahydro pyridine derivatives from aryl-1,8-naphthyridines and indolines, was developed. This method proceeds with unprecedented synthetic effectiveness including high step-economic fashion together with the advantages of having no by-product and no need for external high-pressure H2 gas, offering an important basis for the transformation of 1,8-naphthyridines and indolines into functionalized products.

Funder

2023 Jiangsu Degree and Postgraduate Education Teaching Reform project

2023 Jiangsu Graduate Research and Practice Innovation plan

Funding for School-level Research projects of Yancheng Institute of Technology

2023 Excellent Graduation Project (Thesis) Cultivation project of Yancheng Institute of Technology

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/28/23/7886/pdf

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