Experiments and Calculation on New N,N-bis-Tetrahydroacridines-Reference-Cited by-同舟云学术

Experiments and Calculation on New N,N-bis-Tetrahydroacridines

Published:2024-08-28 Issue:17 Volume:29 Page:4082
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Hrubaru Madalina-Marina¹²^ORCID,Draghici Constantin¹,Ngounoue Kamga Francis Aurelien³,Diacu Elena⁴,Egemonye ThankGod C.⁵^ORCID,Ekennia Anthony C.⁶^ORCID,Ungureanu Eleonora-Mihaela⁴

Affiliation:

1. “C. D. Nenitzescu” Institute of Organic and Supramolecular Chemistry, Romanian Academy, Bucharest, Sector 6, Splaiul Independentei 202B, P.O. Box 35-108, 060023 Bucharest, Romania

2. Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 1-7 Polizu Street, Sector 1, 011061 Bucharest, Romania

3. Coordination Chemistry Laboratory, Department of Inorganic Chemistry, Faculty of Science, University of Yaounde, Yaounde P.O. Box 812, Cameroon

4. Doctoral School Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 1-7 Polizu Street, Sector 1, 011061 Bucharest, Romania

5. Department of Pure and Applied Chemistry, Faculty of Physical Sciences, University of Calabar, Calabar 540281, Cross River State, Nigeria

6. Department of Chemistry, Alex Ekwueme Federal University, Ndufu-Alike, P.M.B. 1010, Abakiliki 482131, Ebonyi State, Nigeria

Abstract

Tetrahydroacridines arouse particular interest due to the potential possibilities of application in the medical field and protection against corrosion. Bis-tetrahydroacridines were newly synthesized by Pfitzinger condensation of 5,5′-(ethane-1,2-diyl) diindoline-2,3-dione with several cyclanones. NMR, MS, and FT-IR were used to prove their molecular structure. In addition, a computer-aided study was performed for the lowest energy conformers of each structure, in vacuum conditions, at ground state using DFT models to assess their electronic properties. UV–Vis and voltammetric methods (cyclic voltammetry, differential pulse voltammetry, and rotating disk electrode voltammetry) were used to investigate their optical and electrochemical properties. The results obtained for these π-conjugated heteroaromatic compounds lead to the conclusion that they have real potential in applications in different fields such as pharmaceuticals and especially as corrosion inhibitors.

Publisher

MDPI AG

Link

https://www.mdpi.com/1420-3049/29/17/4082/pdf

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