Abstract
This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Reference165 articles.
1. Latest Global CANCER Data: Cancer Burden Rises to 18.1 Million New Cases and 9.6 Million Cancer Deaths in 2018,2018
2. Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
3. The re-emergence of natural products for drug discovery in the genomics era
4. Pharmacometrics of Stilbenes: Seguing Towards the Clinic
5. Concentration of the phytoalexin resveratrol in wine;Siemann;Am. J. Enol. Vitic.,1992
Cited by
48 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献