Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues

Author:

Ferraz da Costa Danielly C.,Pereira Rangel LucianaORCID,Martins-Dinis Mafalda Maria Duarte da Cunha,Ferretti Giulia Diniz da Silva,Ferreira Vitor F.,Silva Jerson L.ORCID

Abstract

This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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