Recent Advances in the Research on Luotonins A, B, and E

Author:

Gettler Ján1,Markovič Martin1,Koóš Peter1ORCID,Gracza Tibor1ORCID

Affiliation:

1. Department of Organic Chemistry, Institute of Organic Chemistry, Catalysis and Petrochemistry, Slovak University of Technology, Radlinského 9, SK-812 37 Bratislava, Slovakia

Abstract

This digest review summarises the most recent progress in the study on luotonins A, B and E. The literature covered in this overview spans from January 2012 to April 2024 and presents synthetic methodologies for the assembly of the quinolinopyrrolo-quinazoline scaffold, the structural motifs present in luotonins A, B, and E, and the evaluation of the biological activities of their derivatives and structural analogues.

Funder

Slovak Research and Development Agency

Publisher

MDPI AG

Reference46 articles.

1. Two New Pyrroloquinazolinoquinoline Alkaloids from Peganum nigellastrum;Nomura;Heterocycles,1997

2. Two New Quinazoline-Quinoline Alkaloids from Peganum nigellastrum;Nomura;Heterocycles,1999

3. Alkaloids and phenylpropanoids from Peganum nigellastrum;Ma;Phytochemistry,2000

4. Novel quinazoline-quinoline alkaloids with cytotoxic and DNA topoisomerase II inhibitory activities;Ma;Bioorg. Med. Chem. Lett.,2004

5. Triterpenoids and Alkaloids from the Roots of Peganum Nigellastrum;Ma;Nat. Prod. Commun.,2008

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