Phytochemical Characterizations of Maranthes polyandra (Benth.) Prance

Author:

Ali Nida,Khan Farooq-AhmadORCID,Salawu Kayode Muritala,Irshad Rimsha,Jabeen Almas,Zhang Chun-Lei,Choudhary Muhammad Iqbal,Liu Xin-Min,Wang Yan

Abstract

Two new ursane-type triterpenoids, named Polyanside A (1) and B (2), along with eleven known compounds (3–13), were isolated and elucidated from Maranthes polyandra (Benth.) Prance. The structures of these compounds were elucidated based on chemical evidence and multiple spectroscopic data. Isolated compounds were evaluated for anti-cancer, anti-inflammatory activities, and cytotoxicity on a normal human cell line (BJ). None of them showed activity and cytotoxicity. The hexane fraction was analyzed by GC-MS, resulting in the identification of forty-one compounds. This is the first comprehensive study on the phytochemistry of M. polyandra.

Funder

National Administration of Traditional Chinese Medicine, P. R. China

Higher Education Commission, Pakistan

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Triterpenoids and saponins in drug discovery;Privileged Scaffolds in Drug Discovery;2023

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